Mild traumatic brain injury (mTBI), including sport-related concussion, has become a major health issue. Nearly 10% of mTBI patients (aged 0-18 years) are symptomatic with post-concussion syndrome (PCS) three months after injury. Persistent post-concussion symptoms often result in significant disability and family burden. However, the biological explanation for these prolonged PCS symptoms remains unclear.

The objective of A-CAP is to improve ability to diagnose pediatric concussion and make prognostic predictions about outcomes. A-CAP is a multi-site, prospective cohort study that is assessing a broad pool of neurobiological and psychosocial markers,