Predicting Persistent Postconcussive Problems in Pediatrics (5P)
Predicting Persistent Postconcussive Problems in Pediatrics (5P)
One-third of children with concussion have ongoing physical, thinking, emotional or behavioral symptoms beyond one month, known as persistent post-concussion symptoms (PPCS). PPCS may result in missed school, depressed mood, and lower quality of life. In the Predicting Persistent Postconcussive Problems in Pediatrics (5P) study, the Pediatric Emergency Research (PERC) concussion team developed a PPCS risk score that was significantly better than the child’s physician at predicting future PPCS. The score incorporates nine clinical variables containing information from demographics, past medical history, initial signs and symptoms, and physical examination. Clinicians are now able to provide accurate information to patients and families regarding the expected recovery, and researchers may target children at high risk for PPCS in new trials with the goal of preventing PPCS.
Funding
Canadian Institute of Health Research, Ontario Neurotrauma Foundation, CHEO Foundation, University of Ottawa
Co-Investigators
- Dr. Peter Anderson, CHEO, Psychology
- Dr. Karen Barlow, ACH Neurology,
- Dr. Nick Barrowman, CHEO RI, Biostatistician
- Dr. Miriam Beauchamp, University of Montreal, Psychology
- Dr. Darcy Beer, Manitoba, Pediatric Emergency
- Dr. Kathy Boutis, HSC, Pediatric Emergency
- Dr. Brian Brooks, ACH, Psychology
- Dr. Emma Burns, IWK, Pediatric Emergency
- Dr. William Craig, Stollery, Pediatric Emergency
- Dr. Carol DeMatteo, McMaster, Rehabilitation
- Dr. Sasha Dubrovsky, MCH, Pediatric Emergency
- Dr. Ken Farion, CHEO, Pediatric Emergency
- Dr. Stephen Freedman, ACH Pediatric Emergency
- Dr. Isabelle Gagnon, MCH, Rehabilitation
- Dr. Jocelyn Gravel, HSJ, Pediatric Emergency
- Dr. Blaine Hoshisaki, University of Ottawa, Kinesiology
- Dr. Michelle Keightley, University of Toronto, Psychology
- Dr. Terry Klassen, Manitoba, Pediatric Emergency
- Dr. William Meehan, Harvard University, Sports medicine
- Dr. Willem Meeuwisse, Unversity of Calgary, Sports medicine
- Dr. Angelo Mikrogianakis, ACH, Pedatric Emergency
- Dr. Lawrence Richer, Stollery, Neurology
- Dr. Gurinder Sangha, London, Pediatric Emergency
- Dr. Michael Vassilyadi, CHEO, Neurosurgery
Participating Centres
- Pediatric Emergency Research Canada Concussion (PERC);
- Alberta Children’s Hospital, Calgary, Canada;
- Stollery Children’s Hospital, Edmonton, Alberta, Canada;
- Winnipeg Children’s Hospital, Winnipeg, Manitoba, Canada;
- Children’s Hospital of Western Ontario, London, Canada;
- Hospital for Sick Children, Toronto, Ontario, Canada;
- Children’s Hospital of Eastern Ontario, Ottawa, Canada;
- Montreal Children’s Hospital, Montréal, Quebec, Canada;
- Centre Hospitalier Universitaire Sainte Justine, Montreal, Quebec, Canada;
- IWK Children’s Hospital, Halifax, Nova Scotia, Canada.